More than a dozen bacterial species among the hundreds that live in people’s mouths have been linked to a 50% increased chance of developing head and neck squamous cell carcinoma (HNSCC), a new study shows.
The new analyses, which followed participants for 10 to 15 years, looked at the genetic makeup of oral microbes collected from healthy men and women. Of the hundreds of different bacteria that are routinely found in the mouth, 13 species were shown to either raise or lower risk of HNSCC.
Overall, this group was linked to a 30% greater likelihood of developing the cancers. In combination with five other species that are often seen in gum disease, the overall risk was increased by 50%.
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Gum disease is more common in individuals with microvascular complications of diabetes, new research published in The Journal of Dental Research has found.